Top 19 US AI Startups Securing $100M+ Funding in 2025: Innovation at Its Finest!
The artificial intelligence (AI) industry experienced a remarkable year in 2024, with a surge in funding that has set the stage for continued growth in 2025. In the first half of this year, AI startups in the U.S. are already showing signs of maintaining the momentum, making it an exciting time for investors and innovators alike.
Major Funding Rounds in the AI Sector
In 2024, a total of 49 AI startups secured funding rounds exceeding $100 million, according to TechCrunch. Notably, seven companies raised rounds valued at $1 billion or more, including:
- Three startups raised multiple “megarounds.”
- Numerous billion-dollar rounds were closed in Q1 2025, surpassing Q1 2024 levels.
Highlights of AI Funding in 2025
As 2025 unfolds, several significant funding rounds have already been completed, showcasing the robust interest in AI technology. Here’s a summary of notable funding activities:
- SandboxAQ – Closed a $450 million Series E round on April 4, 2025, bringing its valuation to $5.7 billion. Investors included Nvidia and Google.
- Runway – Raised $308 million in a Series D round on April 3, 2025, valuing the company at $3 billion.
- OpenAI – Announced a record-breaking $40 billion funding round on March 31, 2025, valuing the company at $300 billion.
- Nexthop AI – Secured $110 million in a Series A round on March 25, 2025.
- Insilico Medicine – Raised $110 million for its innovative drug discovery platform on March 13, 2025.
- Celestial AI – Completed a $250 million Series C round on March 11, 2025, raising its valuation to $2.5 billion.
- Lila Sciences – Raised $200 million in a seed round focused on developing a scientific superintelligence platform.
- Reflection.Ai – Valued at $580 million after raising $130 million in a Series A round.
- Turing – Closed a Series E round on March 7, 2025, valued at $2.2 billion.
- Shield AI – Raised $240 million in a Series F round on March 6, 2025.
- Anthropic – Announced a Series E round of $3.5 billion on March 3, 2025, bringing its valuation to $61.5 billion.
Funding Rounds from Earlier Months
In addition to the impressive rounds in March and April, the following funding activities occurred in February and January:
- Together AI – Closed a $305 million Series B round on February 20, 2025.
- Lambda – Raised $480 million in a Series D round on February 19, 2025.
- Abridge – Valued at $2.75 billion after a $250 million Series D round on February 17, 2025.
- Eudia – Secured $105 million in a Series A round on February 13, 2025.
- EnCharge AI – Raised $100 million in a Series B round on February 13, 2025.
- Harvey – Completed a $300 million Series D round on February 12, 2025.
- ElevenLabs – Secured $180 million in a Series C round on January 30, 2025.
- Hippocratic AI – Closed a $141 million Series B round on January 9, 2025.
With these funding milestones, the AI sector is poised for further advancements and innovations as 2025 progresses. Stay updated on the latest trends by visiting TechCrunch AI.
This article has been updated as of April 23, 2025, to include the latest funding news.
